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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2001 3
2003 6
2004 10
2005 3
2007 1
2008 1
2011 1
2012 1
2013 2
2016 1
2017 3
2018 3
2019 3
2020 2
2021 1
2024 0

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39 results

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Page 1
IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.
Rajurkar M, Dang K, Fernandez-Barrena MG, Liu X, Fernandez-Zapico ME, Lewis BC, Mao J. Rajurkar M, et al. Cancer Res. 2017 Jan 15;77(2):320-329. doi: 10.1158/0008-5472.CAN-15-1684. Epub 2017 Jan 9. Cancer Res. 2017. PMID: 28069799 Free PMC article.
Loss of IKBKE inhibits the initiation and progression of pancreatic tumors in mice carrying pancreatic-specific KRAS activation. ...Interestingly, combined inhibition of IKBKE and mTOR synergistically blocks pancreatic tumor growth. Together, our findings highlight …
Loss of IKBKE inhibits the initiation and progression of pancreatic tumors in mice carrying pancreatic-specific KRAS activation. ...I …
IL-17 axis accelerates the inflammatory progression of obese in mice via TBK1 and IKBKE pathway.
Lee SH, Jhun J, Byun JK, Kim EK, Jung K, Lee JE, Choi JY, Park SH, Cho ML. Lee SH, et al. Immunol Lett. 2017 Apr;184:67-75. doi: 10.1016/j.imlet.2017.02.004. Epub 2017 Feb 22. Immunol Lett. 2017. PMID: 28237848
IL-17 also showed up-regulation of mRNA levels of inflammatory cytokines in RAW cells. The inhibitor of TBK1 and IKBKE attenuates the effect of IL-17. Loss of IL-17 deficiency improves diet-induced obesity, fatty liver, glucose and lipid metabolism in mice. The expression …
IL-17 also showed up-regulation of mRNA levels of inflammatory cytokines in RAW cells. The inhibitor of TBK1 and IKBKE attenuates the …
IKBKE regulates cell proliferation and epithelial-mesenchymal transition of human malignant glioma via the Hippo pathway.
Lu J, Yang Y, Guo G, Liu Y, Zhang Z, Dong S, Nan Y, Zhao Z, Zhong Y, Huang Q. Lu J, et al. Oncotarget. 2017 Jul 25;8(30):49502-49514. doi: 10.18632/oncotarget.17738. Oncotarget. 2017. PMID: 28548934 Free PMC article.
IKBKE is increased in several types of cancers and is associated with tumour malignancy. ...Furthermore, we constructed nude mouse subcutaneous and intracranial models to verify that IKBKE could attenuate U87-MG tumourigenicity in vivo. ...
IKBKE is increased in several types of cancers and is associated with tumour malignancy. ...Furthermore, we constructed nude mouse su …
Defects in the interferon-gamma and interleukin-12 pathways.
Rosenzweig SD, Holland SM. Rosenzweig SD, et al. Immunol Rev. 2005 Feb;203:38-47. doi: 10.1111/j.0105-2896.2005.00227.x. Immunol Rev. 2005. PMID: 15661020 Review.
The IFN-gamma/IL-12 pathway is central in immune control of both environmental and autochthonous challenges, as reflected in human mutations and animal models. Besides being crucial for mycobacterial control, the IFN-gamma/IL-12 pathway is also involved in the patho …
The IFN-gamma/IL-12 pathway is central in immune control of both environmental and autochthonous challenges, as reflected in human mutations …
Dexrazoxane ameliorates radiation-induced heart disease in a rat model.
Li L, Nie X, Zhang P, Huang Y, Ma L, Li F, Yi M, Qin W, Yuan X. Li L, et al. Aging (Albany NY). 2021 Jan 2;13(3):3699-3711. doi: 10.18632/aging.202332. Epub 2021 Jan 2. Aging (Albany NY). 2021. PMID: 33406500 Free PMC article.
We investigated the effects of dexrazoxane, a USFDA-approved cardioprotective drug administered with chemotherapy, on radiation-induced heart disease (RIHD) in a rat model. Male Sprague-Dawley rats were irradiated with a single dose of 20 Gy to the heart and treated with d …
We investigated the effects of dexrazoxane, a USFDA-approved cardioprotective drug administered with chemotherapy, on radiation-induced hear …
Long non-coding RNA cytoskeleton regulator RNA (CYTOR) modulates pathological cardiac hypertrophy through miR-155-mediated IKKi signaling.
Yuan Y, Wang J, Chen Q, Wu Q, Deng W, Zhou H, Shen D. Yuan Y, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1421-1427. doi: 10.1016/j.bbadis.2019.02.014. Epub 2019 Feb 19. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30794866 Free article.
Moreover, miR-155 was significantly related to hypertrophic cardiomyopathy (HCM, |hsa05410) and predicted to target both CYTOR and IKBKE. Luciferase reporter and RIP assays revealed that CYTOR served as a ceRNA for miR-155 to counteract miR-155-mediated repression of IK …
Moreover, miR-155 was significantly related to hypertrophic cardiomyopathy (HCM, |hsa05410) and predicted to target both CYTOR and IKBKE …
NF-kappaB: a key role in inflammatory diseases.
Tak PP, Firestein GS. Tak PP, et al. J Clin Invest. 2001 Jan;107(1):7-11. doi: 10.1172/JCI11830. J Clin Invest. 2001. PMID: 11134171 Free PMC article. Review. No abstract available.
Ostreolysin induces browning of adipocytes and ameliorates hepatic steatosis.
Nimri L, Staikin K, Peri I, Yehuda-Shnaidman E, Schwartz B. Nimri L, et al. J Gastroenterol Hepatol. 2018 Dec;33(12):1990-2000. doi: 10.1111/jgh.14259. Epub 2018 May 15. J Gastroenterol Hepatol. 2018. PMID: 29663549
BACKGROUND AND AIM: Non-alcoholic fatty liver disease (NAFLD) is associated with all features of the metabolic syndrome. ...
BACKGROUND AND AIM: Non-alcoholic fatty liver disease (NAFLD) is associated with all features of the metabolic syndrome. ...
IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDS.
Heckmann A, Waltzinger C, Jolicoeur P, Dreano M, Kosco-Vilbois MH, Sagot Y. Heckmann A, et al. Am J Pathol. 2004 Apr;164(4):1253-62. doi: 10.1016/S0002-9440(10)63213-0. Am J Pathol. 2004. PMID: 15039214 Free PMC article.
Wasting and renal diseases are frequent complications of HIV (human immunodeficiency virus) infection and are associated with accelerated disease progression and increased mortality. Transgenic mice expressing HIV1 under control of the CD4 promoter develop an AIDS-like …
Wasting and renal diseases are frequent complications of HIV (human immunodeficiency virus) infection and are associated with accelerated …
39 results